#Penicillin allergy cross reactivity professional

How many people have a penicillin allergy?Īpproximately 10% of the population in the United States reports a drug allergy to beta-lactam antibiotics, making it the most commonly reported drug allergy nationwide. But we’re going to shatter this textbook urban legend for practical, real-world practice purposes.Īlright, now that we’ve got that out of the way, let’s dive into a little background. If you’re taking any sort of board exam (i.e., NAPLEX, MPJE, etc.), you should definitely operate under the assumption that there is a one-size-fits-all cross-reactivity between all beta-lactams when selecting answer choices. I suppose now would be the best time for me to insert a disclaimer. Universal cross-reactivity between beta-lactams (penicillins, cephalosporins, and carbapenems) is essentially an urban legend that we’ve all been taught by textbooks. There are a lot of misconceptions surrounding beta-lactam and penicillin allergies. (Kernicterus is a unique effect with ceftriaxone, particularly when used in neonates.)īut what if I told you there was more than one correct answer choice here? Which would you think is most likely to also be correct?Īlthough not by the technical NAPLEX study guide, answer choice A is also correct! Which is NOT a cephalosporin class effect? Imagine you are taking a quiz during your Infectious Diseases block and you come across this question: Post-residency, she plans on taking some time to catch up on sleep before embarking on the hunt for a clinical position. (Insert shameless Twitter plug - Outside of pharmacy, she tends to her collection of succulent plants, spends time with family and friends, and enjoys traveling to explore new places.

#Penicillin allergy cross reactivity professional

Her professional interests are primarily all things infectious diseases and antimicrobial stewardship, but she’s also interested in a little bit of everything. She is a New Orleans native and graduated from Xavier University of Louisiana College of Pharmacy in New Orleans, LA. Shelby Gross, PharmD is finishing up her PGY-1 residency at University Medical Center New Orleans. Here to feed us the blue (or was it red?) pill to show us behind the beta lactam Matrix is Shelby Gross.